Health & Wellness

On ‘Treated with Dr. Sara,’ Meet the NFL Player Making Longevity Testing Affordable for Everyone

Bernadette Giacomazzo
October 7, 2025
Jimmy St. Louis on Tearing Down Barriers to Longevity Testing
Image: Katie Huber-Rhoades/Dupe

On Treated with Dr. Sara, host Dr. Sara Szal goes beyond the gridiron with former Tennessee Titans tight end Jimmy St. Louis. Instead of talking about touchdowns, St. Louis talks about something that affects every single one of us: how to live longer, healthier lives. 

Today, the doors of longevity clinics are often guarded by wealth, with wellness packages resembling luxury vacations more than healthcare. But this exclusivity didn’t sit right with St. Louis. As the CEO of Agentis Longevity, where Dr. Sara also serves on the medical advisory board, his mission is to tear down these barriers and bring preventative care and health optimization to everyone. 

Jimmy St. Louis on Tearing Down Barriers to Longevity Testing

Why Jimmy St. Louis believes everyone deserves longevity care  

St. Louis knows firsthand the privilege of having access to elite-level health testing. As a pro athlete, his performance was tracked down to the smallest detail.

But he doesn’t think that kind of care should be limited to athletes. “I just believe everybody needs access to their healthcare information, their labs, just understand what’s going on,” he says. “And I think everybody needs to understand good nutrition, gut health, what’s going on with your hormones, and what makes you feel a certain way.” 

He’s referring to the type of baseline data that indicates how your body is aging. At Agentis, St. Louis has identified five key tests he believes everyone should have access to: comprehensive biomarkers, grip strength assessment, cognitive function testing, coronary artery calcium scoring, and body composition analysis. Together, these create what he calls a “composite health score”—a single number that shows where you stand and informs your next steps. In simpler terms, this baseline data is like a health report card that tells you how your body is doing and what you can do to improve it.

More than just “nice-to-haves” for the ultra-wealthy, these tools provide information that could help millions of people add healthier years to their lives.

The power of early mornings and discipline 

Discipline has always been at the core of St. Louis’s story. “I believe from the ages of 11 until 17, there was not a single day I didn’t wake up before 5:30 in the morning,” he recalls. That same early-morning discipline that carried him through football and rowing now drives his approach to healthcare: identify the mission, measure progress daily, remove barriers.

Even more important than discipline is what he’s chosen to do with it: impact over exclusivity. “What is success in your mind? To me, success is making a difference for other people,” St. Louis explains. His mission is not just about providing care, but about changing lives and reshaping the future of healthcare. 

Building a framework that works for everyone

At the heart of his mission are four values: family, fitness, faith, and mission. He compares them to the four legs of a stool. “If you think about losing faith and something terrible happens in your family, where do you go back to? Sometimes terrible things happen, and you go back to faith. If something terrible happens to your health, where do you go?” he explains. “You lean on your mission, and you lean on your family to help support you.”

For St. Louis, creating simple and accessible systems of care that keep people balanced and supported before major health crises occur is key. But beyond affordability and democratizing longevity care, he hopes to spark a paradigm shift—one where middle America understands that longevity care is for them, too. 

Changing the culture around longevity 

That commitment to accessibility is evident in even the smallest choices. St. Louis recently gave up alcohol altogether and encouraged his team to celebrate with non-alcoholic, nootropic alternatives instead of beer. Nootropic alternatives are drinks or supplements that are believed to enhance cognitive function and are also often used as a healthier substitute for alcohol.

“Party culture is ending. And I think it’s a beautiful thing,” he says. For him, that’s another aspect of the cultural shift: moving from a reactive to a preventative approach, from indulgence to optimization. 

Longevity shouldn’t be reserved for billionaires and pro athletes. St. Louis knows what it’s like to have access to data about every part of his body. Now, he also wants to make sure the rest of us do, too. As he puts it, “I just believe in doing the baseline things first. Everyone should do that. Everyone should have access to good nutrition, some level of physical fitness, and a sense of community. And then go and work to start to optimize.”

Ultimately, Jimmy St. Louis hopes that his legacy lies in rewriting the rules of who ages well, rather than on the gridiron.


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