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(171 episodes)Diagnosed With Stage 3 Breast Cancer at 19: Miranda McKeon’s Story
Miranda McKeon was only 19 when she noticed a lump in her breast and was diagnosed with stage three, hormone positive, HER2 negative invasive ductal carcinoma.
In honor of Breast Cancer Awareness Month, Miranda joins SheMD to share the full story of her diagnosis, treatment and life after breast cancer. She opens up about the breast dimpling she initially dismissed, learning she carried a CHEK2 mutation despite having no family history of cancer, freezing her eggs before chemotherapy, undergoing a double mastectomy and radiation, and entering medically induced menopause in her early 20s.
Miranda also talks candidly about painful sex, vaginal dryness, low libido, dating, body image, fertility and the emotional impact of experiencing cancer during what should have been her college years.
Dr. Thaïs Aliabadi explains breast changes women should pay attention to, how genetics and breast density can affect risk, and why knowing your own baseline and speaking up when something changes can matter.
This conversation is a powerful reminder that breast cancer does not only affect older women and that knowing your body is an important part of advocating for your health.
Subscribe to SHE MD Podcast for expert tips on PCOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women’s health and well-being.
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What You'll Learn
Why breast cancer rates are rising faster in women under 50, and why young women's symptoms are so often dismissed.The early signs of breast cancer beyond a lump, including skin dimpling, nipple changes, discharge, and persistent one-sided flaky skin.How CHEK2 mutations and polygenic risk scores shape breast cancer risk, even without a family history.Why a one-size-fits-all mammogram age misses individual risk, and how breast density, family history, and genetics change the picture.How to calculate your lifetime breast cancer risk with the Tyrer-Cuzick model and when high-risk screening should begin.How chemotherapy can affect fertility, and why egg freezing should come before treatment.What medically induced menopause looks like for a young woman, including hot flashes, low libido, and vaginal dryness.How vaginal estrogen and CO2 laser treatments can help with painful sex.How to cope emotionally with a young-onset diagnosis, from therapy to gratitude lists to a trusted inner circle.Key Takeaways
Breast cancer is more common after 50, but rates are rising faster in younger women, and one in six new invasive cases occurs before age 50.Skin dimpling and other changes are symptoms too. A young woman may not recognize them as warning signs, which can delay diagnosis.Most women diagnosed with breast cancer have no family history, so a lack of family history is not a guarantee of low risk.Mammograms starting at 40 treat everyone alike. Breast density, genetics, family history, and polygenic risk can all change when screening should begin.Every woman should know her lifetime breast cancer risk by 30. A risk of 20% or more means earlier imaging, which may include mammogram, ultrasound, and MRI.Egg freezing should be part of the first conversation before chemotherapy, because chemo's effect on ovarian reserve is unpredictable.Medically induced menopause can bring severe symptoms, including painful sex, and women shouldn't feel ashamed to bring them up with their doctors.A double mastectomy leaves some residual breast tissue, so ongoing monitoring is still important.Know what's normal for your breasts and report changes promptly.Therapy, gratitude, and a trusted circle can help you get through a young-onset diagnosis.Guest Bio - Miranda McKeon
Miranda McKeon is a breast cancer survivor, women’s health advocate, and content creator who was diagnosed with stage 3 hormone-positive, HER2-negative invasive ductal carcinoma at just 19 years old. After discovering a lump in her breast while home from college, Miranda underwent chemotherapy, a double mastectomy, radiation, and medically induced menopause. She later learned that she carries a CHEK2 genetic mutation associated with an increased risk of breast cancer.
Since her diagnosis, Miranda has become an outspoken advocate for young women navigating cancer, sexual health, fertility, body image, and life after treatment. She openly shares her experience with intimacy and medically induced menopause and uses her platform to encourage women to understand their bodies and advocate for their health.
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Whitney Cummings: Freezing My Eggs, “Geriatric Pregnancy,” and Becoming a Mom at 40
This one is a full-circle moment. Our guest isn't just one of Mary Alice's oldest friends (25 years and counting), she's also one of Dr. A's real-life patients, the doctor who actually froze her eggs. Whitney Cummings, comedian, actress, and creator of 2 Broke Girls and Whitney, has built a career saying the things women usually only whisper about. Today she says them out loud, with us.
Whitney was talking about freezing her eggs before it was a mainstream conversation (she did it at 33), and she is refreshingly, hilariously honest about getting pregnant at 40, being handed the term "geriatric pregnancy," the postpartum depression that came after her son, and the body image struggles she's carried for years. She and the hosts get into fertility, the real cost of waiting, why "biology is sexist," and the money advice she gives every young woman (skip the designer bag, save it for your eggs).
Funny, tender, and the kind of honesty that makes you feel less alone.
Subscribe to SHE MD Podcast for expert tips on PCOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women's health and well-being.
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What You'll Learn
Why Whitney froze her eggs at 33 and how it eased her anxiety about dating and timing.Why Dr. A tells patients never to use all of their frozen eggs to make embryos with a partner.How egg quantity and quality decline with age, and what that means for miscarriage risk.The lifestyle changes Whitney made before conceiving naturally at 40.The testing and monitoring Dr. A recommends for advanced maternal age pregnancies, including preterm birth screening, low-dose aspirin, and growth ultrasounds.Why delivery at 39 weeks is recommended for women over 40.The difference between postpartum blues and postpartum depression, and how long the postpartum period really lasts.Whitney's approach to co-parenting, forgiveness, and choosing a partner.Key Takeaways
Egg freezing can reduce the pressure and anxiety around timing, and women should always keep some of their own eggs rather than using them all for embryos with a partner.Both egg quantity and quality decline with age, but many women still have healthy pregnancies in their 40s with the right care and awareness of their personal risk factors.Advanced maternal age pregnancies benefit from closer monitoring, including preterm birth screening, low-dose aspirin, regular growth ultrasounds, and delivery at 39 weeks.Postpartum depression affects about one in seven women, can appear up to a year after birth, and is more likely without strong support at home.Asking for help, leaning on your village, and letting motherhood change you are essential parts of postpartum recovery.Choosing a partner based on respect and integrity, and co-parenting with kindness, creates a healthier environment for your child.Guest Bio - Whitney Cummings
Whitney Cummings is a comedian, actress, director, and writer. She is the co-creator of 2 Broke Girls, the creator and star of NBC's Whitney, and the host of the podcast Good for You. Known for her disarmingly honest stand-up specials, Whitney has spoken openly about egg freezing, body image, sobriety, and her recovery from an eating disorder. She became a mom at 40 to her son Henry and has been candid about her pregnancy and postpartum journey.
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Female Longevity: Hormones, Midlife, Brain Health & Aging Strong with Dr. Elizabeth Poynor
What does it actually mean to age well as a woman?
Dr. Elizabeth Poynor joins SheMD to explore longevity through a female and hormonal lens. Drawing on her background in gynecologic oncology, cancer prevention and women’s health, she explains why midlife can be a critical turning point and what may begin changing in the body years before menopause.
Dr. Poynor breaks down the roles of estrogen, progesterone and testosterone, including their connections to sleep, mood, brain fog, body composition, metabolic health and overall well-being. She also discusses hormone therapy, GLP-1s, protein intake, strength training, genetic testing, cancer prevention and why she believes movement is one of the most important habits women can build for long-term health.
Plus, Dr. Poynor shares her own experience with BRCA1, why she believes women should take a more proactive approach to prevention, and the mindset shift she wants women to make about aging.
Midlife is not just something to get through. It may be one of your greatest opportunities to take control of how you age.
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What You’ll Learn
Why midlife is a critical window for women to take a proactive approach to longevity and healthHow hormonal changes in the late reproductive years can affect sleep, mood, brain health, metabolism, and body compositionThe role of strength training, protein, sleep, nutrition, and stress management in healthy agingWhat women should know about hormone therapy, including estrogen, progesterone, and testosteroneHow GLP-1 medications may fit into midlife health and body composition, and why maintaining muscle is so importantWhy women’s longevity needs to be understood through a hormonal lens—and where more research is still neededKey Timestamps
00:00 Welcome to SHE MD Podcast
00:41 From Oncologist To Longevity Expert
04:04 Why Cancer Rates Are Rising
05:11 Genetic Testing And BRCA Story
07:47 Foundational Pillars For Health
09:42 Protein Intake For Midlife Women
11:44 GLP-1s And Body Composition
19:19 The Midlife Hormonal Turning Point
26:44 When To Start Hormone Therapy
31:46 Oral Vs Transdermal Estrogen
41:07 Progesterone And Testosterone Explained
46:37 Why Midlife Is A Critical Window
50:03 Movement As The Top Longevity Habit
51:12 Peptides: Where The Research Stands
53:10 Women's Longevity Vs Men's
Key Takeaways
Midlife is a critical opportunity to take a proactive approach to health and longevity.Hormonal changes can impact sleep, mood, brain health, metabolism, and body composition.Strength training and daily movement are foundational for healthy aging.Protein and muscle preservation become increasingly important as women age.Hormone therapy should be personalized and discussed with a knowledgeable healthcare professional.More research is needed on hormones, GLP-1s, peptides, and women’s longevity.Healthy habits built earlier in life can create a stronger foundation for long-term health.Women’s longevity should be studied through a female-specific hormonal lens.Guest Bio - Dr. Elizabeth Poyner
Dr. Elizabeth Poynor is a board-certified gynecologic oncologist, pelvic surgeon, and women’s health expert specializing in menopause, hormone health, and complex gynecologic conditions. She is Chair of Women’s Health and Gynecology at the Atria Health and Research Institute and a Clinical Professor at NYU Grossman School of Medicine. She combines her expertise in gynecologic oncology, surgery, and midlife women’s health to help women better understand and navigate their health.
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Kim Kardashian’s Trainer Senada Greca: Why Women Shouldn’t Fear Heavy Weights
Muscle is having its moment, and the woman leading the charge trains one of the most famous bodies in the world. Senada Greca, Kim Kardashian's trainer, joins Dr. A and Mary Alice to make the case that strength is a woman's birthright, and that lifting heavy will not make you bulky. It will make you powerful, capable, and built to last.
Senada shares how she went from using exercise to punish her body to using it to build herself, and how strength training became a tool that helped her heal. She and the hosts get into why so many of us were taught to fear the weight rack, what strength really does for your bones, your brain, and your longevity as you age, and how to start moving from a place of love instead of punishment.
Her advice for every woman listening: move, move mindfully, and move heavy.
Follow SheMD and share this with a woman who's ready to feel strong. @SheMDPodcast, shemdpodcast.com
Content note: this conversation includes an honest discussion of disordered eating and recovery. If you're struggling, please reach out to someone you trust or a qualified professional.
This podcast is for educational and entertainment purposes only and is not a substitute for medical advice. Some products or services discussed may involve sponsorships or paid advertising..
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What You’ll Learn
Why women shouldn’t be afraid of lifting heavy weights and why strength training won’t automatically make you bulkyHow strength training can support muscle mass, bone health, cognitive health, and longevity as women ageHow to start strength training safely, from mastering basic movements to gradually increasing weightWhy progressive overload and proper form matter more than how much weight you can liftHow protein, carbohydrates, and creatine can support strength, muscle, and overall healthHow to shift your relationship with exercise from punishment to a way of caring for and building your bodyHow strength can translate beyond the gym into greater confidence, capability, and trust in yourselfKey Timestamps
00:00 Welcome to SHE MD Podcast
01:29 Her Battle With Anorexia & Binge Eating
03:35 The Shift From Punishment to Strength
07:04 Kim's 5x a Week Heavy Lifting Revealed
07:51 Why Women Are Terrified of Weights
10:14 Progressive Overload Explained
19:01 How Beginners Should Start Lifting
23:18 "Will Lifting Make Me Bulky?" Myth Busted
25:35 Muscle, Bone Density & Alzheimer's Link
25:46 Why Protein Is Non-Negotiable
28:11 Sonata's Daily Protein & Creatine Ritual
40:41 Free Resources for Beginners
47:46 Farmer's Carries, Age & Menopause
Key Takeaways
Start where you are. Even five minutes of movement can help build a consistent habit.Focus on moving well and mindfully before adding more weight.Strength training is about becoming stronger and more capable, not shrinking yourself.Gradually increasing the challenge, while maintaining good form, is key to building strength.Aim for consistency over perfection. Three intentional strength-training sessions per week can be effective.Protein is an important part of supporting muscle growth and strength, particularly as women get older.Strength training becomes increasingly important for supporting muscle and bone health as we age and move through perimenopause and menopause.Movement can be an act of self-care: move to protect your future self, support your longevity, and build trust in your body.As Senada puts it: move, move mindfully, and move heavy.Guest Bio - Senada Greca
Senada Greca is a certified personal trainer, breathwork and meditation teacher, and the strength coach behind Kim Kardashian's viral heavy-lifting transformation. After overcoming her own struggle with anorexia, binge eating, depression, and anxiety, she built her career around helping women reframe fitness as a tool for strength rather than punishment. She holds an MBA and is the founder of We Rise, a fitness and self-development platform and app that combines strength training with mental health support, career development, and community-building for women.
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Rhea Seehorn: The Secret to Healthy Co-Parenting
Rhea Seehorn is up for an Emmy this weekend for her extraordinary performance in Pluribus, so we're bringing back one of our most personal, most-loved episodes. Because to Mary Alice, Rhea isn't just an award-winning actress. She's her best friend, and the stepmom to her two boys.
In this conversation, Mary Alice and Rhea tell the wild (and very true) story of how they met, and how Mary Alice ended up setting Rhea up with her own ex-husband. They get honest about building a thriving blended family over twelve years, co-parenting after divorce, dating in your 30s, the female friendships that hold everything up, and the health scare a dozen doctors waved off as "probably hormonal" before Rhea pushed for a real answer. She closes with five pieces of hard-won advice every woman needs to hear, starting with "you're already enough."
Whatever happens on Emmy night, we could not be prouder of her.
A companion to our episode with parenting coach Betsy Brown Braun. Follow SheMD and share this with a woman navigating divorce, dating, or a blended family of her own. @SheMDPodcast ·shemdpodcast.com
This podcast is for educational and entertainment purposes only and is not a substitute for medical advice. Some products or services discussed may involve sponsorships or paid advertising.
Subscribe to SHE MD Podcast for expert tips on PMOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women’s health and well-being.
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Key Timestamps
00:00 Welcome to SHE MD Podcast
04:24 Rhea’s Dating Advice
08:17 Choosing Not to Have Biological Children
11:52 Building a Blended Family
16:45 Friendship, Confidence & Supporting Other Women
18:38 The Hardest Part of a Blended Family
21:37 Missing Moments With Your Kids
23:17 Becoming a “Bonus Mom”
24:52 Balancing Motherhood & a Career
27:09 How Rhea Seehorn Became an Actress
30:00 Building a Career in Hollywood
33:42 Better Call Saul & Career-Defining Roles
37:18 Rhea’s Career, Family & Life Today
40:15 Final Thoughts
Key Takeaways
How to co-parent without chaos: Whether biological or step-parent, your love and presence matter.Making a blended family work: boundaries, respect, and lots of grace. Accept that blended families require flexibility and compromise.Women need to stop apologizing for ambition: Working moms can be great role models by pursuing their passions.Speak up at the doctor’s office: Push for proper medical care, especially when facing dismissive responses.Open communication: Express needs and boundaries to strengthen relationships.Guest Bio: Rhea Seehorn
Rhea Seehorn is an Emmy-nominated actress and director best known for her acclaimed performance as Kim Wexler in Better Call Saul. She currently stars as Carol Sturka in Pluribus, earning a 2026 Emmy nomination for Outstanding Lead Actress in a Drama Series. Before acting, Rhea studied visual art and discovered theater through an acting elective in college, eventually building a career across theater, comedy, television, and drama. In this episode of SHE MD, Rhea joins her close friend Mary Alice Haney for a deeply personal conversation about dating, becoming a stepmother, building a blended family, choosing not to have biological children, balancing motherhood with a demanding career, and the path that ultimately led her to acting.
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PCOS: The Signs Your Doctor Might Be Missing
NOTE: PCOS is now called PMOS, or Polycystic Metabolic Ovarian Syndrome.
PMOS is about so much more than irregular periods or fertility. In this episode of SheMD, Dr. Thaïs Aliabadi breaks down the four major pillars of PCOS, and explains how they can all be connected.
This is a deep dive into why PCOS is so often missed, the symptoms that can look different from woman to woman, the role insulin resistance can play, and why you don’t necessarily need high testosterone or polycystic appearing ovaries to meet the criteria for PCOS.
Dr. A also explains how PCOS can affect weight, acne, hair growth, mood, brain fog, ovulation, fertility, and long-term health, plus what women and parents of teenage girls should know about getting properly evaluated.
If you’ve ever wondered whether your symptoms could be connected, this episode is your PCOS deep dive.
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The New Perimenopause: A Masterclass with Dr. Mary Claire Haver
The frozen shoulder. The 3 a.m. anxiety. The brain fog and the rage that come out of nowhere. For decades, women were told it was "just stress" and sent home with an antidepressant. This week, Dr. A and Mary Alice welcome back the woman changing that — Dr. Mary Claire Haver, the OB-GYN The New York Times calls the "Menopause Queen" — for a full masterclass on perimenopause.
It can start in your late 30s, it lasts 7 to 10 years, and almost no one warned us. Dr. Haver explains what's really happening in your body and brain, why so many women are dismissed, and what you can actually do about it — HRT, progesterone, vaginal estrogen, sleep, mood, and the myth that you have to wait until it's "bad enough" to get help. Because suffering isn't the price of admission.
Subscribe to SHE MD Podcast for expert tips on PMOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women’s health and well-being.
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What You’ll Learn
What perimenopause actually is and how it differs from menopauseWhy perimenopause can begin in your late 30s or 40sWhy brain fog, sleep disruption, anxiety and mood changes can be early symptomsWhen hormone therapy may be considered during perimenopauseThe difference between HRT/MHT, birth control and vaginal estrogenWhat we know, and still don't know, about HRT and cardiovascular and bone healthHow GLP-1 medications can affect muscle and bone healthThe role of protein, resistance training, vitamin D, omega-3s, fiber and creatineWhat declining estrogen can mean for vaginal and urinary healthWhat women should know about HRT and breast cancer riskWhy listening to your symptoms and advocating for yourself mattersKey Timestamps
00:00 Why Every Vagina Needs Estrogen
01:32 Welcome Back Dr. Mary Claire Haver
05:44 What Perimenopause Actually Is
08:44 The "Zone Of Chaos" And Brain Glitching
18:08 How To Evaluate A Perimenopausal Patient
20:01 All Vaginas Need Estrogen
24:50 Why Perimenopause Is The Best Time To Start HRT
32:13 GLP-1s, Muscle Loss, And Bone Health
36:41 Patches, Pellets, Creams: What Actually Works
40:23 Debunking The HRT-Breast Cancer Myth
50:33 Creatine, Vitamin D, And Key Supplements
54:56 The Histamine-Hormone Connection
58:12 Vulvar Changes Nobody Warns You About
1:04:37 Lightning Round: Hormone Myths Busted
1:07:19 Three Takeaways For Every Woman
Key Takeaways
Perimenopause is a years-long biological transition, not simply the period immediately before menopause.Symptoms can appear before periods become irregular or hot flashes begin.Brain fog, sleep disruption and mental health changes can be among the earliest signs of fluctuating hormones.Hormone therapy does not necessarily have to wait until a woman is fully menopausal; treatment should be individualized based on symptoms, risks and benefits.Bone health, cardiovascular health, muscle mass and metabolic health all deserve attention during the menopause transition.If using GLP-1 medications, Dr. Haver emphasizes adequate protein, resistance training and monitoring body composition rather than focusing solely on the number on the scale.Vaginal and urinary symptoms can be related to declining estrogen and may be treated with local estrogen therapy.The goal of understanding perimenopause is not simply to get through it, but to enter the next stage of life informed, healthy and empowered.Guest Bio: Dr. Mary Claire Haver
Dr. Mary Claire Haver is a board-certified OB-GYN and a leading voice in menopause and women's health. She has dedicated her career to helping women better understand the biological changes that happen during midlife and has been called the “Menopause Queen” by The New York Times. She is the author of the bestselling The New Menopause and her newest book, The New Perimenopause, which focuses on the years leading up to menopause. She also hosts the podcast Unpaused and shares women's health education across social media.
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